Premature Baby

New Study Shows Steroid Treatment for Preemies’ Lungs Has No Long-Term Negative Effects

A recent study published in Pediatrics this month examined the potential long-term effects of using steroids on premature infants to strengthen their lungs. The study concluded that preemies between 28 and 32 weeks are not negatively affected by this treatment, which was previously thought to cause brain damage.

tiny premature baby in NICU

In the past, there were concerns about the safety of multiple courses of steroids for pregnant women in preterm labor. However, this study suggests that these worries may have been unfounded. Dr. Sanjiv Amin, the author of the study, explains that the consensus in recent years has been to limit steroid treatment to one course in order to avoid potential adverse effects. However, this approach often results in more babies needing ventilation upon birth.

Breathing difficulties are a major challenge for preterm babies. Their lungs often lack a protective film called surfactant, which causes respiratory distress syndrome. As a result, these infants may require medication and supplemental oxygen, which can lead to complications such as bronchopulmonary dysplasia.

Previous studies linked neurological issues to the use of dexamethasone, a steroid prepared with sulfur. However, the current study focused on infants who received betamethasone, a sulfur-free steroid, and found no adverse effects. This suggests that the type and timing of the steroids may play a role in the outcomes.

The study analyzed data from 174 babies born between 1996 and 1998 and found no significant differences in brain development between infants who received one course of steroids and those who received two or more courses. The only notable difference was that infants who received more courses were less likely to require mechanical ventilation immediately after birth.

These findings are promising and may provide a tool to improve the chances of survival for preterm babies. However, more research is needed to fully understand the safety and effectiveness of multiple courses of steroids.

Overall, this study sheds light on the potential benefits of steroid treatment for preemies, debunking previous concerns about brain damage. Further studies will help determine the best course of action for ensuring the health and well-being of these fragile infants.


 

About the author

Lisa Arneill

Founder of Growing Your Baby and World Traveled Family. Canadian mom of 2 boys, photo addict, lover of bulldogs, and museumgoer. Always looking for our next vacation spot!

1 Comment

  • That’s a great study but it looks like it’s referring to prenatal steroid treatment, not steroid treatment in neonatal infants.

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